Nerve Muscle Physiology Exam Questions for Under Graduates: MBBS


LONG ESSAYS (10 Marks)
  1. Explain RMP and How RMP is maintained.
  2. Explain the structure of Neuro-muscular junction with a neat diagram. Give the sequence of events in transmission of nerve impulses through the NMJ
  3. Describe Excitation-Contraction Coupling in skeletal muscle .What is the phenomenon of muscle fatigue?
  4. Define Action potential. Explain the various phases & ionic basis of nerve action potential with a suitable diagram.

SHORT ESSAYS (5 Marks)
  1. Strength-Duration curve
  2. Saltatory conduction
  3. Erlanger and Gasser classification of nerve fibers
  4. Ionic basis of nerve action potential
  5. Explain the changes during Wallerian degeneration and regeneration of injured nerve fiber
  6. Molecular basis of skeletal muscle contraction
  7. Resting membrane potential
  8. Refractory period
  9. Neuromuscular blockers
  10. Walk along mechanism for contraction of skeletal muscle
  11. Give the differences between skeletal muscle and smooth muscle
  12. Define action potential. Explain  the various phases of nerve action potential
  13. Differences between isotonic & isometric contraction
  14. Neuro- muscular junction
  15. Excitation-Contraction coupling
  16. End plate potential
  17. Differences between skeletal and cardiac muscle
  18. Draw a neat labeled diagram of a spinal motor neuron
  19. Neuroglia
  20. Myasthenia gravis
  21. Sarcotubular system
  22. Properties of a nerve fiber
  23. Motor unit.        

SHORT ANSWERS (5 Marks)
  1. Draw and label a Sarcomere in the relaxed state
  2. Muscle proteins
  3. Chronaxie and Rheobase
  4. Saltatory conduction
  5. Strength duration curve
  6. Fatigue
  7. Distal changes in axon following nerve injury
  8. Tetanus and Clonus
  9. Myasthenia Gravis
  10. All or none law
  11. Difference between Action potential and local potential
  12. Define motor unit
  13. Oxygen Debt
  14. Define resting membrane potential. Give the normal values of Rmp of nerve, skeletal, cardiac and smooth muscle
  15. Define the following terms:
  16. Action potential
  17. End plate potential
  18. Miniature end plate potential

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